Author

Shrijana Shrestha

Patan Academy of Health SciencesORCID 0000-0001-9484-0227Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:whole-genome sequencing· 3 Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andrew John PollardiD· 4 shared David R. MurdochiD· 2 shared Dominic F. KellyiD· 2 shared John A. LeesiD· 2 shared Meeru GurungiD· 2 shared Michael James CarteriD· 2 shared Samuel HorsfieldiD· 2 shared Sonu Shrestha· 2 shared

Activity by Year

2018-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersGenomics

Andrew John PollardORCID

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4 papers

Recent·Most cited

GenomicsGenome MedicinePeer-reviewedSep 7, 2026

A reusable model of pangenome selection informs optimal surveillance strategies over vaccine introductions

Leonie Johanna Lorenz, Joel Hellewell, Samuel Horsfield…·John A. Lees

The paper develops a mathematical model to predict vaccine replacement dynamics in Streptococcus pneumoniae and identifies optimal genomic surveillance strategies.

DOI 10.1186/s13073-026-01672-4

humanwhole-genome sequencing

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Genetic & Genomic MedicinemedRxivPreprintJul 16, 2026

Genome-wide association study of susceptibility to pneumococcal carriage amongst children

Rama Kandasamy, Meeru Gurung, Sonu Shrestha…·Andrew John Pollard

This study identifies genetic loci associated with pneumococcal carriage in children through a genome-wide association analysis.

DOI 10.64898/2026.07.13.26356474

humanGWAS summary statistics

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GenomicsbioRxivPreprintApr 7, 2026

Global population structure and phase variation of serotype 12F Streptococcus pneumoniae following the introduction of pneumococcal conjugate vaccine

Thi N M Huynh, Alannah C. King, Jason Chen Qixiang…·Stephanie W. Lo

This study characterizes the global population structure and genetic diversity of serotype 12F Streptococcus pneumoniae, identifying strand-slippage mutations as a mechanism for capsule variation and vaccine evasion.

1 citation

humanwhole-genome sequencing

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Molecular BiologyPLoS neglected tropical diseasesPeer-reviewedApr 23, 2018

Laboratory and Molecular Surveillance of Paediatric Typhoidal Salmonella in Nepal: Antimicrobial Resistance and Implications for Vaccine Policy

Carl Britto, Zoe A. Dyson, Sebastián Duchêne…·Andrew John Pollard

This study analyzes Salmonella isolates from Nepali children to assess antimicrobial resistance and inform vaccine policy.

76 citationstop 1%

humanwhole-genome sequencing

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