Author

Sonu Shrestha

Patan Academy of Health Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:variant calling· 2 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Andrew John PollardiD· 4 shared Celina JiniD· 2 shared Christoph J. BlohmkeiD· 2 shared Hazel DobinsoniD· 2 shared Malick M. GibaniiD· 2 shared Sagida BibiiD· 2 shared Shrijana ShresthaiD· 2 shared Thomas C. DartoniD· 2 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Andrew John PollardORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genome-wide association study of susceptibility to pneumococcal carriage amongst children

Rama Kandasamy, Meeru Gurung, Sonu Shrestha, Sagida Bibi, Stephen Thorson, Michael James Carter, Daniel O’Connor, David R. Murdoch, Dominic F. Kelly, Shrijana Shrestha, Michael Levin, Andrew John Pollard

This study identifies genetic loci associated with pneumococcal carriage in children through a genome-wide association analysis.

medRxiv · Jul 16, 2026 · PreprintGenetic & Genomic Medicine

Global population structure and phase variation of serotype 12F Streptococcus pneumoniae following the introduction of pneumococcal conjugate vaccine

Thi N M Huynh, Alannah C. King, Jason Chen Qixiang, Kathryn M Mulvihill, Hayley Demetriou, Kate C. Mellor, Rebecca A. Gladstone, Gemma G. R. Murray, Oliver Lorenz, Harry C. H. Hung, Teodora Mateeva, Sonu Shrestha, Sarah A. Kelly, Andrew John Pollard, Shrijana Shrestha, , Stephanie W. Lo

This study characterizes the global population structure and genetic diversity of serotype 12F Streptococcus pneumoniae, identifying strand-slippage mutations as a mechanism for capsule variation and vaccine evasion.

bioRxiv · Apr 7, 2026 · PreprintGenomics

Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers

Amber Barton, Jennifer W Hill, Sagida Bibi, Liye Chen, Claire Jones, Elizabeth A. Jones, Susana Camara, Sonu Shrestha, Celina Jin, Malick M. Gibani, Hazel Dobinson, Claire S. Waddington, Thomas C. Darton, Christoph J. Blohmke, Andrew John Pollard

The paper identifies genetic variants and HLA types associated with susceptibility to enteric fever in human volunteers challenged with Salmonella.

Infection and Immunity · Mar 7, 2022Peer-reviewedGenetics

Diagnostic host gene signature to accurately distinguish enteric fever from other febrile diseases

Christoph J. Blohmke, Julius Müller, Malick M. Gibani, Hazel Dobinson, Sonu Shrestha, Soumya Perinparajah, Celina Jin, Harri Hughes, Luke Blackwell, Sabina Dongol, Abhilasha Karkey, Fernanda Schreiber, Derek Pickard, Buddha Basnyat, Gordon Dougan, , Thomas C. Darton

The paper identifies a host gene signature using machine learning to distinguish enteric fever from other febrile diseases with high accuracy.

EMBO Molecular Medicine · Aug 30, 2019Peer-reviewedMolecular Biology