NeurosciencebioRxivPreprint
Protein disulphide isomerase (PDI) is protective against several types of DNA damage, including that induced by amyotrophic lateral sclerosis-associated mutant TDP-43 in neuronal cells/ in vitro models
Sina Shadfar, Marta Vidal, Sonam Parakh…·Julie D. Atkin
This study shows PDI protects neuronal cells from DNA damage caused by etoposide, H2O2, or mutant TDP-43, and localizes to DNA damage sites in the nucleus.
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