Agent-based modeling demonstrates how target-independent processes supplement killing by antibody-drug conjugates in cancer therapy
Melissa C. Calopiz, Jennifer J. Linderman, Greg M. Thurber
This paper uses an agent-based model to show that immune activation and target-independent mechanisms significantly contribute to the efficacy of the ADC T-DXd in cancer therapy.
PLoS Computational Biology · May 26, 2026Peer-reviewedSystems Biology