Author

Michael P. Lynch

University of LimerickORCID 0000-0001-9535-6461Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Aedín C. CulhaneiD· 2 shared Laurent GattoiD· 2 shared Yufei WangiD· 1 shared

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2024-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersBioinformatics

Aedín C. CulhaneORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 6, 2025

Enabling reproducible and reusable genetic demultiplexing benchmarking with Nextflow and Apptainer

Michael Patrick Lynch, Laurent Gatto, Aedín C. Culhane

The paper introduces demux_bench, a reproducible and portable pipeline for benchmarking genetic demultiplexing methods in scRNA-seq using Nextflow and Apptainer.

DOI 10.1101/2025.08.06.668897

scRNA-seqexperimental assay

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BioinformaticsbioRxivPreprintApr 22, 2024

demuxSNP: supervised demultiplexing scRNAseq using cell hashing and SNPs

Michael P. Lynch, Yufei Wang, Laurent Gatto, Aedín C. Culhane

demuxSNP improves demultiplexing in scRNA-seq by combining cell hashing with SNP data, outperforming existing methods on low-quality data.

1 citation

humanscRNA-seq

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