Synthetic BiologyFrontiers in PharmacologyPeer-reviewed
A synthetic Notch (synNotch) system linking intratumoral immune-cancer cell communication to a synthetic blood biomarker assay
Yanghao Fu, TianDuo Wang, John Andrew Ronald
This paper develops a synthetic Notch system that links intratumoral immune-cancer cell communication to a blood biomarker assay by engineering T cells to secrete a detectable protein upon antigen binding.
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