Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference
Javier J. Castro Alvarez, Maxime Revel, Judit Carrasco, Fabienne Cléard, Daniel Pauli, Valérie Hilgers, François Karch, Robert K. Maeda
The paper shows that the iab-8 ncRNA represses downstream genes in the CNS via ELAV-mediated transcriptional interference, with CNS specificity achieved through a 3' extension of the transcript.
PLoS Genetics · Nov 15, 2021Peer-reviewedGenetics