Author

Eiji Nakata

Institute of Advanced Energy, Kyoto UniversityORCID 0000-0001-9564-6805Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:simulation· 1

Frequent Co-Authors

Colin J. JacksoniD· 1 shared Dhani Ram MahatoiD· 1 shared Ferran FeixasiD· 1 shared Morito SakumaiD· 1 shared Nobuhiko TokurikiiD· 1 shared Sílvia OsunaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBiochemistry

Colin J. JacksonORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMay 2, 2026

Single-Molecule Kinetic Exploration of Functional Substates in an Evolving Phosphotriesterase

Morito Sakuma, Dhani Ram Mahato, Ferran Feixas…·Nobuhiko Tokuriki

This study investigates how functional and conformational substates change during enzyme evolution using single-molecule kinetic assays and simulations, showing coordinated shifts in substate equilibria that optimize catalytic efficiency.

2 citations

experimental assaysimulation

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