NeuroscienceNature CommunicationsPeer-reviewed
Enhanced Astrocyte Responses are Driven by a Genetic Risk Allele Associated with Multiple Sclerosis
Gerald D. Ponath, Matthew R. Lincoln, Maya Levine-Ritterman…·David Pitt
The paper shows that the MS risk variant rs7665090G increases astrocyte NF-κB signaling and lymphocyte recruitment, leading to larger MS lesions.
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