Author

Hiromi H Ueda

Kitasato University;ORCID 0000-0001-9586-9339Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:sequence-to-function modeling· 1 Approach:variational autoencoder· 1

Frequent Co-Authors

Aiko Sato· 1 shared Andrejs Tučs· 1 shared Hideji MurakoshiiD· 1 shared Koji TsudaiD· 1 shared Maki Onda· 1 shared Mitsuo UmetsuiD· 1 shared Yutaka SaitoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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1 shared paperNeuroscience

Aiko Sato

Mutual co-authors in cluster

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2 papers

Recent·Most cited

pLM-bVAE: protein language model-enhanced binary representation improves quantum annealing-based protein sequence design

Hiromi H Ueda, Andrejs Tučs, Koji Tsuda, Mitsuo Umetsu, Yutaka Saito

This paper introduces pLM-bVAE, a binary variational autoencoder enhanced with protein language model representations, showing improved sequence reconstruction and design performance in quantum annealing-based protein sequence design.

bioRxiv · Nov 6, 2026 · PreprintBioinformatics

Chronic neuronal excitation leads to homeostatic suppression of structural long-term potentiation

Hiromi H. Ueda, Aiko Sato, Maki Onda, Hideji Murakoshi

This study shows chronic neuronal excitation suppresses structural long-term potentiation (sLTP) through two mechanisms: inhibiting Ca2+ influx and impairing CaMKII downstream signaling.

bioRxiv · Mar 16, 2021 · PreprintNeuroscience