Krishnendu Sinha

The paper shows that warming shifts the transcriptomic age of Anopheles gambiae mosquitoes to an older state without accelerating their ageing pace.

The paper identifies and corrects missed introns in tRNA genes of Asgard archaea, revealing repeated intron gains and their splicing motif preferences.

The paper quantifies repeatable gene retention patterns across independent whole-genome duplications in plants, fungi, and animals, identifying gene-intrinsic factors influencing retention.

The paper introduces Curli Carrier Burden (CCB), a microbiome index quantifying amyloidogenic bacterial signals in Parkinson's disease gut metagenomes, and validates its utility across multiple cohorts.

The paper re-analyzes a transcriptomic scoring pipeline for neurodegeneration axes, finding results sensitive to cell composition and analytic choices, and provides code for improved validation.

BABAPPAlign improves multiple sequence alignment by using a learned residue-level scoring function, outperforming existing tools on standard benchmarks.

BABAPPASnake provides a reproducible workflow for episodic selection analysis with robustness-aware summaries and supports sensitivity tracking across multiple methods.

This study identifies episodic positive selection in Arabidopsis COL3 and COL5 genes, showing adaptive evolution in red-light signaling pathways through specific amino acid substitutions.