ImmunologyImmunityPeer-reviewed
IL-9 signaling redirects CAR T cell fate toward CD8+ memory and CD4+ cycling states, enhancing anti-tumor efficacy
Sofía Castelli, Wesley V. Wilson, Uğur Uslu…·Carl H. June
This study shows that adding IL-9 signaling to CAR T cells improves their anti-tumor effectiveness by shifting their fate toward memory and cycling states.