Leila Kianmehr

The paper integrates metabolomic and transcriptomic data from ADPKD patients to identify metabolic reprogramming linked to cystogenesis and disease progression.

The paper analyzes DNA/RNA hybrid profiles in blood from autistic patients and healthy controls, identifying differences in mRNA and non-coding RNA regions and their regulatory roles.

The paper investigates TERRA-DNA hybrids in psoriasis, finding increased TERRA levels and decreased RNase-HII transcripts, suggesting unresolved DNA/RNA hybrids contribute to genomic instability and skin lesions.

The paper develops a method to detect and isolate stable DNA-RNA triplexes in complex genomes and defines terminal R-loop complexes in mouse and human genomes.