Ex Vivo Expanded Regulatory T Cells Inhibit AAA Progression by Limiting CD4+ and CD8+ T Cell Accumulation in Aortic Tissue
Chandrashekhar Dasari, Jose Luis Lopez, Masood Jan, Sonali S. Shaligram, Pei-Yu Lin, Dina Lévy-Lambert, April Huang, Carlos O. Lizama, Pierce Hadley, Qizhi Tang, Adam Oskowitz
This study shows that ex vivo expanded regulatory T cells reduce CD4+ and CD8+ T cell accumulation in aortic tissue, thereby inhibiting AAA progression in mice.
bioRxiv · Oct 8, 2025 · PreprintImmunology