Bursts in biosynthetic gene cluster transcription are accompanied by surges of natural compound production in the myxobacterium Sorangium sp.
Judith Boldt, Laima Lukoševičiūtė, Chengzhang Fu, Matthias Steglich, Boyke Bunk, Vera Junker, Aileen Gollasch, Birte Trunkwalter, Kathrin I. Mohr, Michael Beckstette, Joachim M. Wink, Jörg Overmann, Rolf Müller, Ulrich Nübel
The paper shows that bursts in biosynthetic gene cluster transcription in Sorangium sp. correlate with natural compound production, challenging the idea that BGCs are preferentially expressed under nutrient limitation.
Microbial Biotechnology · Mar 30, 2023Peer-reviewedGenomics