Author

Chengzhang Fu

Helmholtz Institute for Pharmaceutical Research SaarlandORCID 0000-0002-3513-4768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Rolf MülleriD· 2 shared Aileen Gollasch· 1 shared Birte Trunkwalter· 1 shared Boyke BunkiD· 1 shared Dalei WuiD· 1 shared Feng XieiD· 1 shared Haowen ZhaoiD· 1 shared Jingjun MoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Rolf MüllerORCID

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2 papers

Recent·Most cited

Streptavidins play a multifunctional role within a biotin-pathway antibiotic network encoded in a biosynthetic supercluster

Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu

The paper reveals streptavidin's dual role in sequestering biotin and neutralizing acidomycin, balancing an antibiotic network in microbial competition.

bioRxiv · Nov 10, 2025 · PreprintMicrobiology

Bursts in biosynthetic gene cluster transcription are accompanied by surges of natural compound production in the myxobacterium Sorangium sp.

Judith Boldt, Laima Lukoševičiūtė, Chengzhang Fu, Matthias Steglich, Boyke Bunk, Vera Junker, Aileen Gollasch, Birte Trunkwalter, Kathrin I. Mohr, Michael Beckstette, Joachim M. Wink, Jörg Overmann, Rolf Müller, Ulrich Nübel

The paper shows that bursts in biosynthetic gene cluster transcription in Sorangium sp. correlate with natural compound production, challenging the idea that BGCs are preferentially expressed under nutrient limitation.

Microbial Biotechnology · Mar 30, 2023Peer-reviewedGenomics