NeuroscienceFrontiers in Aging NeurosciencePeer-reviewed
Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression.
Sara J. Fagen, Jeremy D. Burgess, Melina J. Lim…·Pamela J. McLean
This study shows honokiol reduces alpha-synuclein mRNA and protein levels in models of Parkinson's disease by modulating SNCA gene expression, identifying potential therapeutic targets.