Author

Darshana P. Nair

Cornell UniversityORCID 0000-0001-9719-614XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Brian R. CraneiD· 2 shared Angel Malik KahalaiD· 1 shared Chunhao LiiD· 1 shared Kai ZhangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

Brian R. CraneORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 30, 2026

The bacterial swarming factor SwrD belongs to a diverse family of proteins that form hexameric rings

Darshana P. Nair, Kai Zhang, Angel Malik Kahala…·Brian R. Crane

This study characterizes SwrD, a protein involved in bacterial flagellar motor regulation, showing it forms hexameric rings and is conserved across spirochetes.

DOI 10.64898/2026.05.26.727983

bacteria (other)protein structure

𝕏 PostBluesky

BiophysicsbioRxivPreprintAug 15, 2025

Structure and dynamics of a muti-domain nitric oxide synthase regulated by a C2 domain

Darshana P. Nair, Brian R. Crane

This study presents the structural dynamics of a multi-domain nitric oxide synthase regulated by a C2 domain using cryoEM, revealing how pterin binding and Ca2+ influence enzyme conformation and activity.

DOI 10.1101/2025.08.15.670619

structural biologyexperimental assay

𝕏 PostBluesky