A large-scale retrospective study in metastatic breast cancer patients using circulating tumor DNA and machine learning to predict treatment outcome and progression-free survival
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair G. Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gillian Gale, , Carlos Caldas
This study uses ctDNA from metastatic breast cancer patients and a Bayesian model to predict treatment response and progression-free survival, outperforming alternative methods.
bioRxiv · Mar 3, 2023 · PreprintGenomics