Author

Meiling Gao

University of CambridgeORCID 0000-0001-9835-906XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Carlos CaldasiD· 2 shared Emma J. BeddowesiD· 2 shared Maurizio CallariiD· 2 shared Stephen‐John SammutiD· 2 shared Suet‐Feung ChiniD· 2 shared Abdelhamid Boumertit· 1 shared Alistair G. MartiniD· 1 shared Anja BrouweriD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Carlos CaldasORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintMar 3, 2023

A large-scale retrospective study in metastatic breast cancer patients using circulating tumor DNA and machine learning to predict treatment outcome and progression-free survival

Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis…·Carlos Caldas

This study uses ctDNA from metastatic breast cancer patients and a Bayesian model to predict treatment response and progression-free survival, outperforming alternative methods.

1 citation

humanDNA methylation

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Developmental BiologyCell DiscoveryPeer-reviewedSep 27, 2022

Metabolic control of histone acetylation for precise and timely regulation of minor ZGA in early mammalian embryos

Jingyu Li, Jiaming Zhang, Weibo Hou…·Qingran Kong

This study identifies metabolic features in mouse pre-implantation embryos and shows that NAD+ synthesis is essential for development and regulates minor ZGA through H3K27ac erasure.

107 citationstop 1%

mouseproteomics

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GenomicsGenome MedicinePeer-reviewedJan 4, 2019

Next Generation-Targeted Amplicon Sequencing (NG-TAS): An optimised protocol and computational pipeline for cost-effective profiling of circulating tumour DNA

Meiling Gao, Maurizio Callari, Emma J. Beddowes…·Carlos Caldas

NG-TAS is a cost-effective method for profiling ctDNA mutations in cancer patients, showing consistent detection of mutations at >1% allele fraction.

66 citations

humanDNA methylation

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