Shaojun Pei

The paper identifies seven subtypes of ALS motor cortex with distinct molecular programs and shows they are organized by genetic and clinical factors rather than disease duration.

SpaCoEx selects sparse genes for spatially varying co-expression in spatial transcriptomics, improving spatial coherence and annotation agreement in cancer datasets.

This paper introduces a protein embedding model that captures both global and local structural similarity, outperforming existing methods in structural comparison tasks.