Author

Colin Klaus

University of ChicagoORCID 0000-0001-9759-4068Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:diffusion model· 1 Assay:multiome· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Marcos M. SotomayoriD· 2 shared Félix RicoiD· 1 shared Fidan SumbuliD· 1 shared Ismahene MesbahiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBioinformatics

Marcos M. SotomayorORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 13, 2026

Bayesian-Steered Structure Prediction of Mechanical Biomolecules Using Twisted Diffusion

Colin Klaus, Marcos M. Sotomayor

This paper introduces a Bayesian-steered diffusion method for predicting alternative conformations of mechanical biomolecules, demonstrating its ability to reproduce experimentally validated states of various proteins and DNA.

DOI 10.64898/2026.05.11.724187

protein structuredeep learning

𝕏 PostBluesky

BiophysicsOpen Research EuropePeer-reviewedMar 28, 2026

PySteMoDA: An Open Source Python Package for the Analysis of Steered Molecular Dynamics Simulations Data

Ismahene Mesbah, Colin Klaus, Marcos M. Sotomayor…·Félix Rico

PySteMoDA provides an automated tool for analyzing steered molecular dynamics simulations, improving accuracy and accessibility in computational biochemistry and biophysics.

DOI 10.12688/openreseurope.22884.1

multiomedeep learning

𝕏 PostBluesky