Jane Charlesworth

HierCC assigns genomes to hierarchical population structures using core genome MLST, enabling scalable and incremental clustering.

PEPPAN reconstructs bacterial pan- and core-genomes with high accuracy and speed, outperforming existing methods in a case study of Streptococcus genomes.

Severe S. aureus infections arise from the nasal microbiome through adaptive evolution, with specific mutations enriched in infecting bacteria compared to colonizing ones.