Federico Lucchetti

MRSIPrep provides a standardized post-quantification framework for whole-brain MRSI to improve reproducibility across datasets and applications.

The paper uses longitudinal spectroscopic imaging to show sex-specific hormone-metabolite coupling in adolescent brains, revealing age and sex-dependent neurochemical changes.

The paper uses magnetic resonance spectroscopic imaging to identify sex differences in brain metabolites across multiple cohorts, finding a consistent male higher tNAA/tCr ratio in gray and white matter.

This study uses high-resolution 3D-MRSI to assess neurometabolite differences in youth at risk for psychosis compared to controls, finding elevated tNAA and Ins in specific brain regions.

The paper constructs the first human brain metabolic connectome using MR spectroscopic imaging, revealing distinct topological features and alignment with cytoarchitectonic and genetic patterns.