Author

Qinchang Chen

Zhejiang LabORCID 0000-0001-9793-8676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:deep learning· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:large language model· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Guohui ChuaiiD· 2 shared Qi LiuiD· 2 shared Chi ZhouiD· 1 shared Feiyang XingiD· 1 shared He ZhangiD· 1 shared Jin TangiD· 1 shared Jun ZhangiD· 1 shared Liya HouiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Guohui ChuaiORCID

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2 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedNov 19, 2024

Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Wenhui Li, Xianyue Jiang, Wuke Wang…·Qi Liu

The paper introduces CHOOSER, a foundation model-based framework for discovering CRISPR-Cas systems with self-processing pre-crRNA capability, identifying 11 novel homologs and validating one for functional use.

21 citations

proteomicslarge language model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintAug 2, 2023

Neo-epitope identification by weakly-supervised peptide-TCR binding prediction

Yuli Gao, Yicheng Gao, Wannian Li…·Qi Liu

This study introduces TCRBagger, a weakly-supervised framework for peptide-TCR binding prediction to improve neo-epitope identification in tumor immunotherapy.

3 citations

humanscRNA-seq

𝕏 PostBluesky