BiophysicsbioRxivPreprint
Conformational dynamics at the pre-miR-377 Dicer site governs selective small-molecule recognition
Jacopo Manigrasso, Emeline Mestdach, Ricardo quaia…·Giuseppina La Sala
The paper studies how dynamic conformational changes in pre-miR-377's Dicer site enable small-molecule recognition, showing that binding depends on RNA dynamics rather than a single structure.
DOI 10.64898/2026.02.11.705234