Author

Emeline Mestdach

AstraZeneca (Sweden)ORCID 0000-0001-7263-9864Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:structural biology· 2 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Aline Le RoyiD· 1 shared Anders HogneriD· 1 shared Andrey I. FroloviD· 1 shared Caroline MasiD· 1 shared Cécile BreytoniD· 1 shared Claudine DarnaultiD· 1 shared Corinne Deniaud-VivesiD· 1 shared Daniela DankováiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

Aline Le RoyORCID

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2 papers

Recent·Most cited

Superinfection exclusion strategy of siphophage T5: analysis of the FhuA:Llp complex

Séraphine Degroux, Corinne Deniaud-Vives, Emeline Metsdach, Claudine Darnault, Aline Le Roy, Caroline Mas, Loïc Salmon, Torsten Herrmann, Cécile Breyton

The paper determines the structure of Llp and analyzes the FhuA:Llp complex to understand superinfection exclusion in bacteriophage T5.

Journal of Virology · Oct 12, 2026Peer-reviewedBiophysics

Conformational dynamics at the pre-miR-377 Dicer site governs selective small-molecule recognition

Jacopo Manigrasso, Emeline Mestdach, Ricardo quaia, Daniela Danková, Mattias Bood, Malin Lemurell, Stefan Geschwindner, Andrey I. Frolov, Matthew David Disney, Anders Hogner, N. Celestine, Giuseppina La Sala

The paper studies how dynamic conformational changes in pre-miR-377's Dicer site enable small-molecule recognition, showing that binding depends on RNA dynamics rather than a single structure.

bioRxiv · Feb 12, 2026 · PreprintBiophysics