Revealing the impact of recurrent and rare structural variants in multiple myeloma
Even Holth Rustad, Venkata D. Yellapantula, Dominik Głodzik, Kylee H. Maclachlan, Benjamin T. Diamond, Eileen Mary Boyle, Cody Ashby, Patrick Blaney, Gunes Gundem, Malin L. Hultcrantz, Daniel A. Leongamornlert, Nicos Angelopoulos, Daniel Auclair, Yanming Zhang, Ahmet Doǧan, , Francesco Maura
This study identifies 100 SV hotspots and 31 new candidate driver genes in multiple myeloma, revealing that 63% of SVs remain unexplained and are associated with outlier gene expression.
bioRxiv · Dec 18, 2019 · PreprintGenomics