NeurosciencebioRxivPreprint
Ptf1a robustly drives the gliogenic switch in the rodent embryonic cortex in a dosage-dependent manner by activating pro-glial gene expression programs
Haixiang Li, Kaiqin Lu, Xiaoxuan Wang…·Shuijin He
This study shows that Ptf1a drives gliogenesis in rodent embryonic cortex by activating pro-glial gene programs, with dosage-dependent effects on oligodendrocyte production.
DOI 10.1101/2025.10.14.682493