John Aaron Howell

Effects of Global Ripk2 Genetic Deficiency in Aged Mice following Experimental Ischemic Stroke

This study shows that global Ripk2 deletion in aged mice reduces infarct size and improves motor function after ischemic stroke, suggesting RIPK2 as a therapeutic target.

RIPK2 is crucial for the microglial inflammatory response to bacterial muramyl dipeptide but not to lipopolysaccharide

This study shows that RIPK2 is essential for microglial inflammatory responses to MDP but not to LPS.

Elastin-like polypeptide delivery of anti-inflammatory peptides to the brain following ischemic stroke

This study demonstrates that SynB1-ELP-p50i, a drug carrier bound to an NF-κB inhibitor, reduces infarct volume and improves survival in rats after ischemic stroke.