Author

Shaye Carver

Dana-Farber Cancer InstituteORCID 0000-0001-9882-7740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander GuseviD· 2 shared Kodi TaraszkaiD· 2 shared Intae MooniD· 1 shared Jian Carrot‐ZhangiD· 1 shared Stefan GrohaiD· 1 shared Tomin E. Perea-ChambleeiD· 1 shared Xinran Yu· 1 shared Yi DingiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Alexander GusevORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintApr 22, 2026

Meta-Analysis of Rare Cancers Leveraging Clinically Ascertained Cohorts Reveals Novel Germline Susceptibility Loci

Shaye Carver, Tomin E. Perea-Chamblee, Kodi Taraszka…·Alexander Gusev

This study performs GWAS on 20 rare cancers using three cohorts, identifying nine novel susceptibility loci with replication across eight cancer types.

DOI 10.64898/2026.04.16.26350975

humanwhole-genome sequencing

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GenomicsHuman Genetics and Genomics AdvancesPeer-reviewedOct 28, 2025

Discovery of disease-associated cellular states using ResidPCA in single-cell RNA and ATAC sequencing data

Shaye Carver, Kodi Taraszka, Stefan Groha, Alexander Gusev

The paper introduces ResidPCA, a method for identifying cell states in single-cell RNA and ATAC sequencing data, showing improved accuracy over existing methods in both simulated and real datasets.

DOI 10.1016/j.xhgg.2025.100538

mousehuman

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