Molecular BiologybioRxivPreprint
3-phenyllactic acid promotes healthspan through SKN-1/ATFS-1-mediated mitochondrial activation and stress resilience
Juewon Kim, Yunju Jo, Gyumin Lim…·Dongryeol Ryu
This study identifies 3-phenyllactic acid (PLA) as a metabolite from lactic acid bacteria that extends healthspan in C. elegans by enhancing mitochondrial function and stress resilience, and links PLA levels to sarcopenia in humans.
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