Author

Anna Lappala

Harvard UniversityORCID 0000-0001-9926-2972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:dimensionality reduction· 1 Assay:Hi-C· 1 Approach:simulation· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Cameron Tauxe· 1 shared Christina R. SteadmaniD· 1 shared Cullen RothiD· 1 shared David RogersiD· 1 shared Jeannie T. LeeiD· 1 shared Karissa Y. SanbonmatsuiD· 1 shared Shawn R. StarkenburgiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Cameron Tauxe

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1 paper

Recent·Most cited

BioinformaticsBMC BioinformaticsPeer-reviewedJan 8, 2026

From 2D to 4D: a Containerized Workflow and Browser to Explore Dynamic Chromatin Architecture

David Rogers, Cullen Roth, Cameron Tauxe…·Shawn R. Starkenburg

The paper introduces 4DGBWorkflow and 4DGB, open-source tools that use molecular dynamics simulations constrained by Hi-C data to generate 3D chromatin reconstructions and integrate them with epigenomic data for visualization.

2 citations

Hi-Cstatistical model

𝕏 PostBluesky