Neel A Patel

This paper introduces AGNet models to predict TF binding affinity and shows they outperform CNNs and variant annotation tools in classifying impactful non-coding variants.

The paper uses neural network models to detect transcription factor regulatory modules in lymphoblastoid cells and identifies their effects on gene expression.

The paper assesses how well existing human protein 3D structures represent genetic and functional diversity across the 1000 Genomes Project, finding significant underrepresentation of African ancestry sequences.