Molecular BiologybioRxivPreprint
Mechanosensitive activation of mTORC1 mediates ventilator induced lung injury during the acute respiratory distress syndrome
Hyunwook Lee, Qinqin Fei, Adam Streicher…·Joshua A. Englert
This study shows that mTORC1 activation during mechanical ventilation worsens lung injury in ARDS and that inhibiting mTORC1 can prevent ventilator-induced lung injury.