Yutao Dou

This paper introduces a symmetric self-play framework for protein inverse folding that improves sequence design self-consistency by decoupling structural objectives.

The paper introduces EiRA, a generative model for designing proteins that bind biomolecules, achieving state-of-the-art performance across multiple metrics and demonstrating DNA-conditioned binder design.

This paper introduces ESM-DBP, a domain-adapted protein language model for DNA-binding proteins, showing improved prediction performance and interpretability.