Author

Xiaodong Li

Hangzhou Institute of Medicine, Chinese Academy of SciencesORCID 0000-0003-4631-7639Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Bowen LiiD· 1 shared Chulin ShaiD· 1 shared H. Xuanpengfan Zou· 1 shared Shaoliang PengiD· 1 shared Wenwu ZengiD· 1 shared Xiongjun ZhaoiD· 1 shared Yantao LiiD· 1 shared Yutao DouiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Bowen LiORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMar 30, 2026

Symmetric Self-play Online Preference Optimization for Protein Inverse Folding

Wenwu Zeng, Xiaodong Li, H. Xuanpengfan Zou…·Shaoliang Peng

This paper introduces a symmetric self-play framework for protein inverse folding that improves sequence design self-consistency by decoupling structural objectives.

DOI 10.64898/2026.03.26.714453

protein sequencedeep learning

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 18, 2026

CLM-X: A multimodal single-cell foundation model with flexible multi-way Transformer for unified scRNA-seq and scATAC-seq analysis

Bowen Li, Ziqiang Liu, Zhen Wang…·Xiaodong Li

CLM-X is a multimodal single-cell foundation model that outperforms existing methods in cross-modal translation and perturbation prediction across scRNA-seq and scATAC-seq datasets.

1 citation

scRNA-seqscATAC-seq

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