Author

Eleonora Cappelletti

University of PaviaORCID 0000-0002-0004-2193Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Elena GiulottoiD· 5 shared Francesca M. PirasiD· 5 shared Solomon G. NergadzeiD· 4 shared Marialaura BiundoiD· 3 shared Elena RaimondiiD· 2 shared Lorenzo SolaiD· 2 shared Marco SantagostinoiD· 2 shared Adam M. PhillippyiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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5 shared papersGenomics

Elena GiulottoORCID

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Author profile →

5 papers

Recent·Most cited

Unconventional centromere architectures in Tapirus indicus reveal hotspots for satellite-free centromere formation in Perissodactyla

Marialaura Biundo, Francesca M. Piras, Edoardo Rapisarda, Oliver A. Ryder, Solomon G. Nergadze, Elena Giulotto, Eleonora Cappelletti

The paper identifies satellite-free centromeres in Tapirus indicus and shows evolutionary hotspots for such centromeres in Perissodactyla, with uncoupling between CENP-A and CENP-B.

Communications Biology · Jul 7, 2026Peer-reviewedGenomics

Fully Phased Telomere-to-Telomere Assemblies for Thoroughbred Horse and Donkey Haplotypes derived from a Mule Illuminate the Peculiar Evolution of Equid Centromeres

Kai Li, Eleonora Cappelletti, Carey Dessaix, Julia L. Ciosek, Emily D. Robyn, Lauren Johnson, Nahla Hussien AbouEl Ela, Xiomara R. Arias, David L. Adelson, Terje Raudsepp, Francesca M. Piras, Melissa L. Smith, Elizabeth Hudson, Brandon D. Pickett, Sergey Koren, , Ted Kalbfleisch

The paper presents telomere-to-telomere genome assemblies of a Thoroughbred horse and donkey derived from a mule, revealing insights into equid centromere evolution and plasticity.

bioRxiv · Feb 27, 2026 · PreprintMolecular Biology

TERRA transcripts and promoters from telomeric and interstitial sites

Marco Santagostino, Lorenzo Sola, Eleonora Cappelletti, Francesca M. Piras, Nicolò Gennari, Marialaura Biundo, Solomon G. Nergadze, Elena Giulotto

The paper identifies TERRA promoters in subtelomeres and interstitial telomeric sequences, showing their transcriptional activity and contribution to TERRA RNA production.

RNA · Nov 5, 2025Peer-reviewedMolecular Biology

CENP-A/CENP-B uncoupling in the evolutionary reshuffling of centromeres

Eleonora Cappelletti, Francesca M. Piras, Marialaura Biundo, Elena Raimondi, Solomon G. Nergadze, Elena Giulotto

The paper investigates the role of CENP-B in equid centromeres, showing its absence correlates with the loss of CENP-B boxes and the evolution of new centromeric repeats.

bioRxiv · Apr 24, 2024 · PreprintGenomics

Neocentromere formation through Robertsonian fusion and centromere repositioning during the evolution of zebras

Eleonora Cappelletti, Francesca M. Piras, Lorenzo Sola, Marco Santagostino, Wasma A. Abdelgadir, Elena Raimondi, Solomon G. Nergadze, Elena Giulotto

The paper identifies satellite-free neocentromeres in zebras, showing centromere repositioning and Robertsonian fusions contribute to their formation.

bioRxiv · Feb 15, 2022 · PreprintGenomics