Author

Itaru Kushima

Nagoya University Institute for Advanced ResearchORCID 0000-0002-0018-5178Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Norio OzakiiD· 2 shared Aarno V. PalotieiD· 1 shared Alexander KolevzoniD· 1 shared Alfredo BruscoiD· 1 shared Andreas G. ChiocchettiiD· 1 shared Ángel CarracedoiD· 1 shared Antonio Maria PersicoiD· 1 shared Aparna BhaduriiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Norio OzakiORCID

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2 papers

Recent·Most cited

A Network of Networks Approach for Modeling Interconnected Brain Tissue-Specific Networks

Hideko Kawakubo, Yusuke Matsui, Itaru Kushima, Norio Ozaki, Teppei Shimamura

The paper introduces a Network of Networks framework and GOSPEL algorithm to model interconnectivity between brain-specific functional networks and identify autism-associated genetic structures.

Bioinformatics · Jan 11, 2019Peer-reviewedSystems Biology

Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

F. Kyle Satterstrom, Jack A. Kosmicki, Jiebiao Wang, Michael S. Breen, Silvia De Rubeis, Joon‐Yong An, Minshi Peng, Ryan L. Collins, Jakob Grove, Lambertus Klei, Christine R. Stevens, Jennifer G. Reichert, Maureen Mulhern, Mykyta Artomov, Sherif Gerges, , Kaija Puura

This study identifies 99 genes associated with autism spectrum disorder through large-scale exome sequencing, showing differences in mutation frequencies between ASD and severe neurodevelopmental delay groups.

Cell · Jan 1, 2019Peer-reviewedGenetics