Author

Alexander Bryson

The University of MelbourneORCID 0000-0002-0033-8197Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electronic health records· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Steven PetrouiD· 2 shared Bas‐Jan ZandtiD· 1 shared Christian RössertiD· 1 shared Christopher A. ReidiD· 1 shared David Bruce GraydeniD· 1 shared Géza BereckiiD· 1 shared Robert John HatchiD· 1 shared Samuel Frank BerkoviciD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Steven PetrouORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 20, 2023

Biophysical characterization and modeling of SCN1A gain-of-function predicts interneuron hyperexcitability and a predisposition to network instability through homeostatic plasticity

Géza Berecki, Alexander Bryson, Tilman Polster, Steven Petrou

This study characterizes SCN1A gain-of-function variants and models their impact on interneuron hyperexcitability and network instability through homeostatic plasticity in early-onset epileptic encephalopathies.

DOI 10.1101/2023.02.20.529310

humanelectronic health records

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJan 23, 2020

GABA-mediated tonic inhibition differentially modulates gain in functional subtypes of cortical interneurons

Alexander Bryson, Robert John Hatch, Bas‐Jan Zandt…·Steven Petrou

This study shows that GABA-mediated tonic inhibition differentially modulates gain in cortical interneurons based on their electrophysiological properties.

56 citations

electronic health recordsstatistical model

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