Myofiber-specific FoxP1 knockout protects against pancreatic cancer-induced muscle wasting in male but not female mice.
Martin M. Schonk, Jeremy B. Ducharme, Daria Neyroud, Rachel L. Nosacka, Haley O. Tucker, Sarah M. Judge, Andrew R. Judge
This study shows that myofiber-specific FoxP1 knockout prevents pancreatic cancer-induced muscle wasting in male mice but not females, highlighting sex-specific effects of FoxP1 in cancer cachexia.
American Journal of Physiology-Cell Physiology · Nov 15, 2024Peer-reviewedCancer Biology