From General-Purpose to Disease-Specific Features: Aligning LLM Embeddings on a Disease-Specific Biomedical Knowledge Graph for Drug Repurposing
S. C. Pandey, Muhammed Talo, David Peter Siderovski, Nathalie Sumien, Serdar Bozdag
The paper introduces CLEAR, a framework that aligns LLM embeddings with disease-specific knowledge graphs to improve drug repurposing, achieving state-of-the-art results on benchmark datasets.
bioRxiv · Mar 10, 2026 · PreprintBioinformatics