The Maine Coon Cat Harboring the MYBPC3-A31P Mutation: A Genotype-Stratified Phenotypic Characterization of Hypertrophic Cardiomyopathy
Xu Shi, Ruoxuan Li, Zixuan Yang, Yue Wang, Junzhe Huang, Kai Liu, Jing Wang, Liwen Liu, Bo Wang
This study characterizes the phenotypic effects of MYBPC3-A31P mutation in Maine Coon cats, showing gene-dose effects on cardiac structure and function, with homozygous cats exhibiting more severe features.
bioRxiv · Aug 19, 2026 · PreprintGenetics