Author

Kai Liu

ByteDance (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Bioinformatics· 1 Epidemiology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 4 Research Focus:drug response / drug discovery· 2 Assay:protein sequence· 2 Assay:protein structure· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

Alison P Galvani· 1 shared Anew Labs Team· 1 shared Bo WangiD· 1 shared Dandan Cao· 1 shared Gaodeng Li· 1 shared Guangjun Yin· 1 shared Guo‐Bo CheniD· 1 shared Hao GeiD· 1 shared

Activity by Year

2016-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperEpidemiology

Alison P Galvani

Author profile →

5 papers

Recent·Most cited

AnewDDE: An Agentic Drug Discovery Engine for Biomolecular Interaction Modelling and Closed-Loop Design

Anew Labs Team, Kai Liu

AnewDDE integrates AI tools for biomolecular interaction modelling and drug design, demonstrating improved performance in structure prediction, binder identification, affinity estimation, and ADMET prediction.

bioRxiv · Sep 25, 2026 · PreprintBioinformatics

The Maine Coon Cat Harboring the MYBPC3-A31P Mutation: A Genotype-Stratified Phenotypic Characterization of Hypertrophic Cardiomyopathy

Xu Shi, Ruoxuan Li, Zixuan Yang, Yue Wang, Junzhe Huang, Kai Liu, Jing Wang, Liwen Liu, Bo Wang

This study characterizes the phenotypic effects of MYBPC3-A31P mutation in Maine Coon cats, showing gene-dose effects on cardiac structure and function, with homozygous cats exhibiting more severe features.

bioRxiv · Aug 19, 2026 · PreprintGenetics

Programming Biomolecular Interactions with All-Atom Generative Model

Xiangzhe Kong, Junwei Chen, Ziting Zhang, Gaodeng Li, Qingyuan Zhu, L Wei, Mingyu Li, Yan Shi, Weiyang Dai, Zishen Zhang, Wenjuan Tan, Rui Jiao, Xiaolun Wang, Jiqing Zheng, Ziyang Yu, , Jianzhu Ma

This paper introduces AnewOmni, a generative model that designs biomolecules across scales by learning interaction patterns and physical constraints from 5 million complexes.

bioRxiv · Jun 4, 2026 · PreprintBioengineering

Highly Accurate Non-Invasive Preimplantation Genetic Testing for Monogenic and Polygenic Diseases from Spent Medium

Lei Huang, Jin Huang, Minyue Ma, Yangyun Zou, Ruiqi Zhang, Guangjun Yin, Quangui Wang, Yingying Xia, Jialin Jia, Zeyu Wu, Dandan Cao, Weiliang Song, Yaqiong Tang, Kai Liu, Xiaoran Chai, , Xiaoliang Sunney Xie

This paper presents a non-invasive preimplantation genetic testing method using spent embryo culture medium, achieving high accuracy for monogenic and polygenic disease detection without modifying IVF workflows.

medRxiv · Nov 10, 2024 · PreprintGenetic & Genomic Medicine

Real-time Zika risk assessment in the United States

Lauren A Castro, Spencer J Fox, Xi Chen, Kai Liu, Steve E Bellan, Nedialko B Dimitrov, Alison P Galvani, Lauren A Meyers

This paper develops a real-time risk assessment framework for Zika Virus in the US, identifying regions at risk of importation and sustained transmission.

bioRxiv · Sep 7, 2016Epidemiology