Cell BiologybioRxivPreprint
alpha-Actinin-3 deficiency protects from the effects of acute cold exposure through altered skeletal muscle Ca2+ and OXPHOS signaling.
Peter J. Houweling, Chrystal F. Tiong, Leonit Kiriaev…·Kathryn N. North
This study shows that alpha-actinin-3 deficiency improves cold tolerance through enhanced mitochondrial function and reduced muscle mass loss during acute cold exposure.