Coenzyme A is bound to tafazzin - a paradigm change for transacylation
José Guadalupe Rosas Jiménez, Jonathan Schiller, Janet Vonck, Gerhard Hummer, Volker Zickermann
The paper determines the structure of tafazzin and shows coenzyme A is bound to it, revealing a transacylation mechanism and molecular basis for Barth syndrome.
bioRxiv · Feb 7, 2026 · PreprintBiochemistry