Janet Vonck

The paper develops a workflow to predict sidechain conformations of acidic amino acids in cryo-EM maps, validated through Q-score and molecular dynamics simulations.

The paper determines the structure of tafazzin and shows coenzyme A is bound to it, revealing a transacylation mechanism and molecular basis for Barth syndrome.

This study investigates the molecular mechanisms of fungal fatty acid synthase (FAS) assembly, revealing a pathway of domain-domain interactions that underlies its quaternary structure formation.