Author

Sze Lok Alfred Cheng

University of MinnesotaORCID 0000-0002-0102-9812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jeongsik YongiD· 2 shared Wei ZhangiD· 2 shared Ethan J. Beckermann· 1 shared Hyun‐Joo KimiD· 1 shared Jiao SuniD· 1 shared Khandakar Tanvir Ahmed· 1 shared Marella D. CannyiD· 1 shared Meeyeon ParkiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Jeongsik YongORCID

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2 papers

Recent·Most cited

Alternatively-Spliced CAMKK2 isoforms drive differential metabolic stress response and the regulation of ferroptosis

Sze Lok Alfred Cheng, Hyun‐Joo Kim, Naima Ahmed Fahmi, Meeyeon Park, Marella D. Canny, Ritika Kukreja, Ethan J. Beckermann, Michael P. Latham, Wei Zhang, Jeongsik Yong

This study shows that CAMKK2 isoforms LF and SF have distinct roles in metabolic stress response and ferroptosis regulation in cancer cells.

bioRxiv · May 13, 2025 · PreprintBiochemistry

Multi-omics Data Integration by Generative Adversarial Network

Khandakar Tanvir Ahmed, Jiao Sun, Sze Lok Alfred Cheng, Jeongsik Yong, Wei Zhang

This study introduces omicsGAN, a GAN model that integrates multi-omics data and interaction networks to generate synthetic data improving cancer outcome prediction.

Bioinformatics · Aug 18, 2021Peer-reviewedBioinformatics