Author

Abigail W. Bigham

University of California, Los AngelesORCID 0000-0002-0109-5844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 3 Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Kelsey C. JorgenseniD· 2 shared Obed A. GarciaiD· 2 shared Angelis M. Morales Rivera· 1 shared Bartolomeu Acioli‐SantosiD· 1 shared Can AlkaniD· 1 shared Charikleia KarageorgiouiD· 1 shared Christopher A. OsborneiD· 1 shared Chuanzhu FaniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenetics

Kelsey C. JorgensenORCID

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3 papers

Recent·Most cited

Rapid Adaptive Increase of Amylase Gene Copy Number in Indigenous Andeans

Kendra Scheer, Luane J. B. Landau, Kelsey C. Jorgensen, Charikleia Karageorgiou, Lindsey Siao, Can Alkan, Angelis M. Morales Rivera, Christopher A. Osborne, Obed A. Garcia, Laurel Pearson, Melisa Kiyamu, Maria C. Rivera, Fabiola Lèon‐Velarde, Frank S. Lee, Tom D. Brutsaert, , Ömer Gökçümen

The paper identifies a rapid adaptive increase in AMY1 gene copy number in Indigenous Peruvian Andeans linked to potato domestication.

Nature Communications · May 5, 2026Peer-reviewedGenetics

De novo genome assembly of four Andean potato weevil species (Premnotrypes,Rhigopsidius), the primary agricultural pest of the potato in South America

Kelsey C. Jorgensen, Obed A. Garcia, J. Rodriguez Alcazar, Kimberly K. O. Walden, Abigail W. Bigham, Norma Mujica, Clorinda Vergara, Julie J. Lesnik, Chuanzhu Fan

The paper presents de novo genome assemblies for four Andean potato weevil species, identifying genomic regions related to insecticide resistance and host detection.

bioRxiv · Dec 13, 2023 · PreprintGenomics

Hypothetical Human Immune Genome Complex Gradient May Help To Explain The Congenital Zika Symdrome Catastrophe In Brazil: A New Theory

Flávio R. S. Oliveira, Cristiane Campello Bresani-Salvi, Clarice Neuenschwander Lins de Morais, Abigail W. Bigham, Ulisses Braga-Neto, Gladys E. Maestre, j. l. Wandebergh, Ernesto T. A. Marques, Bartolomeu Acioli‐Santos

The paper uses machine learning to identify SNVs in immune genes that distinguish sub-Saharan African and Latin American populations, suggesting a genome gradient that may explain the higher incidence of congenital Zika syndrome in Brazil.

bioRxiv · Jun 3, 2020 · PreprintGenetics