Acetate metabolism during xylose fermentation enhances 3-hydroxypropionic acid production in engineered acid-tolerant Issatchenkia orientalis
Deokyeol Jeong, Dahye Lee, Junli Liu, Soo Rin Kim, Yong‐Su Jin, Jikai Zhao, Eun Joong Oh
This paper engineers an acid-tolerant Issatchenkia orientalis strain to produce 3-hydroxypropionic acid from acetate-rich biomass, achieving 8.7 g/L via separate hydrolysis and fermentation.
Bioresource Technology · Dec 1, 2025Peer-reviewedSynthetic Biology